Tesamorelin Injectable 3ml Vial

Product Description:

TESAMORELIN INJECTABLE 3ML VIAL (8MG/ML)

5 WEEK COURSE- TOTAL 25 SYRINGES

Fat reduction is the major benefit of tesamorelin. In fact, the US Food and Drug Administration approved tesamorelin last November 2010 for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Several lines of evidence clearly support this fat-burning effect:

1. In HIV patients with central fat accumulation, subcutaneous injection of tesamorelin at a dose of 2 mg was generally well tolerated and resulted in sustained decrease in visceral adipose tissue (active component of total body fat). 
2. A 2010 study published in the Journal of Acquired Immune Deficiency Syndromes found that tesamorelin reduced visceral fat (body fat stored within the abdominal cavity) by approximately 18% and improved body image distress in HIV-infected patients with central fat accumulation.
3. A 2011 study published in HIV/AIDS – Research and Palliative Care has shown that tesamorelin is safe and effective in reducing central fat accumulation among HIV-infected patients.
4. In HIV patients with abdominal adiposity, tesamorelin reduced visceral adipose tissue by increasing adiponectin, a protein that breaks down fat.
5. In patients with HIV-related lipodystrophy, 52 weeks of tesamorelin treatment reduced abdominal fat.
6. A 2015 study published in PLoS One Journal found that patients with baseline metabolic syndrome, elevated triglyceride levels, or white race were most likely to experience reductions in visceral adipose tissue following 6 months of tesamorelin treatment.
7. In HIV-infected patients with excess abdominal fat, treatment with tesamorelin reduced visceral adipose tissue and maintained the reduction for up to 52 weeks. 
8. In HIV-infected patients with abdominal fat accumulation, daily tesamorelin treatment for 26 weeks decreased visceral fat by 15.2% compared to placebo.
9. In HIV-infected patients receiving tesamorelin, reduction in visceral adipose tissue was accompanied by improvement in metabolic profile. 

Improves Cognitive Function

Growth hormone–releasing hormone (GHRH) such as tesamorelin has potent effect on brain function. Studies show that this “cognitive enhancer” may benefit people with age-related memory problems and those suffering from chronic, progressive mental deterioration:

1. In older adults with memory impairment, short-term tesamorelin administration improved executive function and verbal memory.
2. Daily subcutaneous injections of tesamorelin for 20 weeks improved executive function, verbal memory, and visual memory in both adults with mild cognitive impairment and healthy older adults.
3. In patients with mild cognitive impairment, tesamorelin administration at a dose of 1mg/day for 10 weeks improved various areas of cognition.
4. A 2012 study published in Nature Reviews Endocrinology found that tesamorelin administration in patients with age-related cognitive impairment significantly improved memory and thinking skills.
5. In adults with mild cognitive impairment, daily subcutaneous injections of tesamorelin increased GH levels and improved executive function and verbal memory.
6. In normal older adults and adults with mild cognitive impairment, tesamorelin administration for 5 months demonstrated favorable effects on cognition. 
7. Self-administration of tesamorelin at 1 mg 30 minutes before bedtime slowed cognitive decline in older adults. 
8. An ongoing Phase II trial of tesamorelin for cognition in aging HIV-infected persons shows promising results with the tesamorelin-treated group exhibiting improvement in neurocognitive performance. 
9. In adults with mild cognitive impairment, administration of daily subcutaneous injections of tesamorelin significantly increased the levels of gamma-Aminobutyric acid (GABA), a neurotransmitter that facilitates brain cell communication. 

Improves Lipid Profile

The ability of tesamorelin to improve lipid profile can be attributed to its fat-burning effect and GH-boosting properties. High-quality studies support its beneficial effect on triglycerides, total cholesterol, low-density lipoprotein (bad cholesterol), and high-density lipoprotein (good cholesterol):

1. In HIV patients with abdominal fat accumulation, subcutaneous injection of tesamorelin at a dose of 2 mg significantly improved triglycerides and total cholesterol levels.
2. The administration of tesamorelin in HIV-infected patients resulted in greater reduction in triglycerides compared to placebo treatment. 
3. Treatment of type 2 diabetic patients with tesamorelin for 12 weeks significantly reduced total cholesterol and low-density lipoprotein.
4. In HIV-infected patients with excess abdominal fat, tesamorelin treatment increased the levels of high-density lipoprotein.
5. In patients with HIV, a daily subcutaneous injection of tesamorelin resulted in decreased visceral fat and improved lipid profiles.

Improves Liver Health

Studies also show that tesamorelin may benefit liver function through various important mechanisms:

1. In HIV-infected men and women with hepatic steatosis (accumulation of fat in the liver), treatment with tesamorelin for 12 months significantly reduced liver fat.
2. In HIV-infected patients with abdominal obesity who received tesamorelin, a clinically significant reduction in body fat was associated with improved liver enzymes.
3. In obese subjects with reduced GH, 12 months of tesamorelin treatment led to a significantly greater increase in phosphocreatine, a substance that protects the liver from low levels of oxygen and impaired blood flow.

Lowers Blood Sugar Levels

Clinical trials also show that tesamorelin can bring down high blood sugar levels by promoting fat loss:

1. The administration of tesamorelin in HIV-infected patients did not only promote abdominal fat loss but also reduce blood sugar levels after 52 weeks of treatment. 
2. Tesamorelin treatment for 26 weeks also reduced blood sugar levels in HIV-infected patients with excess abdominal fat.

Lowers the Risk of Cardiovascular Disease

Evidence suggests that tesamorelin can help reduce the risk of cardiovascular diseases by improving various health parameters such as triglyceride levels and total cholesterol levels. Tesamorelin also has the ability to raise the levels of high-density lipoprotein (good cholesterol). An increase in HDL cholesterol is associated with significant cardiovascular disease risk reduction. 

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